Publications

Please find Dr. Engel’s Google Scholar Profile here.

Papers

  1. R.A. Woldeyes, M. Nishiga, A.S. Vander Roest, L. Engel, et al., Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context. bioRxiv. (2023) https://www.biorxiv.org/content/10.1101/2023.10.26.564098v1
  2. L. Engel, M. Zaoralova, A.R. Dunn, S.L. Oliver. Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes. bioRxiv. (2023) https://doi.org/10.1101/2023.08.05.552110 
  3. W. Cui*, L. Engel*, K.J. Liu, V.T. Vachharajani, C.E. Dundes, S.L. Zheng, M. Begur, K.M. Loh, L. Ang, A.R. Dunn (*equal contribution). A microfluidic platform for anterior-posterior human endoderm patterning via countervailing morphogen gradients in vitro. under review in iScience.
  4. L. Engel*, C.G. Vasquez*, E.A. Montabana, B.M. Sow, M.P. Walkiewicz, W.I. Weis, A.R. Dunn (*equal contribution). Lattice micropatterning for cryo-electron tomography studies of cell-cell contacts. Journal of Structural Biology 213(4), 107791. (2021) https://doi.org/10.1016/j.jsb.2021.107791
  5. M. Garcia, E. Sadeghipour, L. Engel, W.J. Nelson, B.L. Pruitt. MEMS Device for Applying Shear and Tension to an Epithelium combined with Fluorescent Live Cell Imaging. J Micromech Microeng 30 125004. (2020) https://doi.org/10.1088/1361-6439/abb12c
  6. W. Cui*, L. Engel*, C.E. Dundes, T.C. Nguyen, K.M. Loh, A.R. Dunn (*equal contribution). Spatially controlled stem cell differentiation via morphogen gradients: A comparison of static and dynamic microfluidic platforms. Journal of Vacuum Science & Technology A 38 (033205). (2020) https://doi.org/10.1116/1.5142012
  7. L. Engel, G. Gaietta, L.P. Dow, M.F. Swift, G. Pardon, N. Volkmann, W.I. Weis, D. Hanein, B.L. Pruitt. Extracellular matrix micropatterning technology for whole cell cryogenic electron microscopy studies. J Micromech Microeng 29 (11). (2019) https://doi.org/10.1088/1361-6439/ab419a
  8. L. Engel, C. Liu, N. Hemed, Y. Khan, A. Arias, S. Krylov, Y. Shacham-Diamand, L. Lin. Local electrochemical control of hydrogel microactuators in microfluidics. J Micromech Microeng 28 (10), 105005. (2018) https://doi.org/10.1088/1361-6439/aacc31
  9. M. Ben David, L. Engel, Y. Shacham-Diamand. Spectroscopic Ellipsometry Study of Spin Coated P(VDF-TrFE-CTFE) Thin Films and P(VDF-TrFE-CTFE)/PMMA Blends. Microelectronic Engineering. 17, 37-43. (2017) https://doi.org/10.1016/j.mee.2017.01.030
  10. L. Engel*, K.R. Van Volkinburg*, M. Ben-David, G.N. Washington, S. Krylov, Y. Shacham-Diamand (*equal contribution). Fabrication of a self-sensing electroactive polymer bimorph actuator based on polyvinylidene fluoride and its electrostrictive terpolymer. Proc. SPIE 9798, Electroactive Polymer Actuators and Devices (EAPAD), 2016, Las Vegas, Nevada, USA. https://doi.org/10.1117/12.2218383
  11. R. Feiner, L. Engel, S. Fleisher, M. Malki, A. Shapira, Y. Shacham-Diamand, T. Dvir. Engineered hybrid cardiac patches with multifunctional electronics. Nature Materials. (2016)  https://doi.org/10.1038/nmat4590
  12. K. Hakshur*, L. Engel*, Y. Shacham-Diamand, S. Ruschin (*equal contribution). High surface area thermoplastic polymer films fabricated by mechanical tearing using nano-porous silicon. Microelectronic Engineering 150, 71-73. (2016) https://doi.org/10.1016/j.mee.2015.11.003
  13. L. Engel, S. Kruk, J. Shklovsky, S. Krylov, Y. Shacham-Diamand. A study toward the development of an electromechanical poly(vinylidene fluoride-trifluoroethylene-chlorofluoroethylene) buckling membrane actuator. J Micromech Microeng 24 (12), 125027. (2014) https://doi.org/10.1088/0960-1317/24/12/125027
  14. N. Jackson, P. Verbrugghe, D. Cuypers, K. Adesanya, L. Engel, et al. A Cardiovascular Occlusion Method Based on the use of a Smart Hydrogel. IEEE Transactions on Biomedical Engineering 62 (20), 399-406. (2014) https://doi.org/10.1109/TBME.2014.2353933
  15. L. Engel, S. Krylov, Y. Shacham-Diamand. Thermoplastic nano-imprint lithography of electro active polymer poly(vinylidene fluoride-trifluoroethylene-chlorofluoroethylene) for micro/nano scale sensors and actuators. J Micro/Nanolithography, MEMS, and MOEMS 13(3), 033011-033011. (2014) https://doi.org/10.1117/1.JMM.13.3.033011
  16. L. Engel, O. Berkh, K. Adesanya, J. Shklovsky, P. Dubruel, S. Krylov, Y. Shacham-Diamand. Actuation of a novel Pluronic-based hydrogel: Electromechanical response and the role of applied current. Sensors and Actuators B: Chemical 191, 650-658. (2013) https://doi.org/10.1016/j.snb.2013.10.031
  17. J. Shklovsky*, L. Engel*, Y. Sverdlov, S. Krylov, Y. Shacham-Diamand (*equal contribution). Nano-imprinting lithography of P(VDF-TrFE-CFE) for flexible freestanding MEMS devices. Microelectronic Engineering. 100, 41-46. (2012) https://doi.org/10.1016/j.mee.2012.07.112
  18. L. Engel, J. Shklovsky, D. Schreiber, S. Krylov, Y. Shacham-Diamand. Freestanding smooth micron-scale polydimethylsiloxane (PDMS) membranes by thermal imprinting. J Micromech Microeng 22 (4), 045003. (2012) https://doi.org/10.1088/0960-1317/22/4/045003

Patents granted

  1. F. Stam, N. Jackson, P. Dubruel, K. Adensanya, A. Embrechts, E. Mendes, H.P. Neves, P. Herijgers, P. Verbrugghe, Y. Shacham, L. Engel, S. Krylov. Hydrogel based occlusion systems. U.S. Patent Appl. No.: 13/832,069. (2013)
  2. T. Dvir, Y. Shacham-Diamand, R. Feiner, L. Engel. Electronic Scaffold and Uses Thereof. U.S. Patent Appl. No.: 61/905,230. (2014)

Patents submitted

  1. L. Oliver and L. Engel. Affinity capture system for electron microscopy. U.S. Patent Appl. No.: 63/334470. (2022)